Click here to see all the TRIP Evidence Reviews.
Evidence-Based Reports
- Natalizumab reduces relapse and disability in relapsing multiple sclerosis. POEMs, 2006
- Intravenous immunoglobulin for MS. Bandolier, 2005
- Modafinil was a safe treatment for MS fatigue, but its efficacy remains to be determined. Neurology CATs, 2004
- The McDonald's MRI criteria may be useful for the early diagnosis of MS in patients presenting with a clinically isolated neurological syndrome. Neurology CATs, 2004
- Good communication with healthcare providers helped patients with multiple sclerosis to cope and adapt. Evidence-Based Nursing (Requires free registration), 2004
Clinical Guidelines
- Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis. 2005
- EFNS guideline on treatment of multiple sclerosis relapses: report of an EFNS task force on treatment of multiple sclerosis relapses. 2005
- Treatment of Multiple Sclerosis with ß-interferon and Glatiramer Acetate. Association of British Neurologists, 2007
- Management of multiple sclerosis in primary and secondary care. NICE, 2003
Systematic Reviews
- Amantadine for fatigue in multiple sclerosis. Cochrane Database of Systematic Reviews, 2007
- Cyclophosphamide for multiple sclerosis. Cochrane Database of Systematic Reviews, 2007
- Dietary interventions for multiple sclerosis. Cochrane Database of Systematic Reviews, 2007
- Treatment for ataxia in multiple sclerosis. Cochrane Database of Systematic Reviews, 2007
- Mitoxantrone for multiple sclerosis. Cochrane Database of Systematic Reviews, 2005
- Psychological interventions for multiple sclerosis. Cochrane Database of Systematic Reviews, 2005
- Sativex for the management of multiple sclerosis symptoms. Health Technology Assessment, 2005
- Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic review. DARE, 2006
- Home versus outpatient administration of intravenous steroids for multiple-sclerosis relapses: a randomised controlled trial. NHS EED, 2006
Recent articles in core journals
- Longitudinal follow-up of "benign" multiple sclerosis at 20 years. Neurology, 2007
- Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double-blind, placebo-controlled trial. Ann Neurol, 2007
- Effectiveness of non-pharmacological interventions for fatigue in adults with multiple sclerosis, rheumatoid arthritis, or systemic lupus erythematosus: a systematic review. J Adv Nurs, 2006
- Lack of association between antimyelin antibodies and progression to multiple sclerosis. NEJM, 2007
- Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review. Arch Neurol, 2006
- Prognostic factors for early severity in a childhood multiple sclerosis cohort. Pediatrics, 2006
- Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic review. BMJ, 2006
- Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA, 2006
- A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. NEJM, 2006
- Natalizumab plus interferon beta-1a for relapsing multiple sclerosis. NEJM, 2006
- Diagnosis and Management of Multiple Sclerosis. American Family Physician, 2004
eTextbooks
Clinical Queries
- For a woman using combined oral contraception, is there any evidence to suggest a contraindication to the use of Interferon beta for treatment of multiple sclerosis? Faculty of Family Planning & Reproductive Health Care Q&A, 2006
- For a woman who is immobilised as a result of multiple sclerosis, is there any evidence that there may be increased symptoms with a reduction in oestroegn with the use of progestogen only injectables? Faculty of Family Planning & Reproductive Health Care Q&A, 2005
- Should all patients with multiple sclerosis have Vit D levels monitored and be given therapeutic doses if below normal levels to reduce incidence of relapse? NLH Q&A Service, 2005
- Should a patient with multiple sclerosis be given the influenza vaccination? NLH Q&A Service, 2005
- It is recommended that patients with multiple sclerosis have their eyes tested regularly. Are there any published guidelines on how frequently this should be done? NLH Q&A Service, 2006
- How suitable are IUDs (non-hormonal) for patients with multiple sclerosis? NLH Q&A Service, 2006
Patient Information